Clivus Chordoma

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Clivus Chordoma with an arachnoid cyst, coincidence or causative factor?

Clivus chordoma coincidence with arachnoid cyst is rare. We report a rare case of clivus chordoma associated with arachnoid cyst.

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clivus chordoma with an arachnoid cyst, coincidence or causative factor?

the clivus is the surface of a portion of the occipital and sphenoid bones in the base of the skull. (1)it is surrounded by the neurovascular structures of the brainstem, as well as internal carotid arteries. tumors of the clivus can be benign (chordoma)or malignant (chondrosarcoma).(2) chordomas are rare, aggressive, slow-growing, invasive, and locally destructive tumors that arise from the no...

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Surgical Excision of Clivus Chordoma with the Use of Coblator—A Case Report

Chordomas are dysembryogenic tumors originating from the notochordal process [1] [2]. They are aggressive tumours with unique diagnostic and management challenges. Primary therapy is complete surgical removal of the tumour as much as possible. The likelihood of recurrence is high in spite of complete surgical resection. A 52-year-old female patient presented with complaints of decreased vision ...

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Sustained Response of a Clivus Chordoma to Erlotinib after Imatinib Failure

Chordoma is a rare malignant axial tumour that develops from embryonic remnants of the notochord. Surgery and irradiation are the standard initial treatment. However, local recurrence is frequent and cytotoxic chemotherapy is inefficient. Transient activity of imatinib, a platelet-derived growth factor receptor inhibitor, was described in a phase II study. Activity of epidermal growth factor re...

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Experimental Study on Differences in Clivus Chordoma Bone Invasion: An iTRAQ-Based Quantitative Proteomic Analysis

Although a bone tumor, significant differences in the extent of bone invasion exist in skull base chordoma, which directly affect the extent of surgical resection, and have an impact on its prognosis. However, the underlying mechanism of the phenomenon is not clearly understood. Therefore, we used an iTRAQ-based quantitative proteomics strategy to identify potential molecular signatures, and to...

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ژورنال

عنوان ژورنال: Acta Endocrinologica (Bucharest)

سال: 2019

ISSN: 1841-0987,1843-066X

DOI: 10.4183/aeb.2019.406